Document Type

Journal Article

Department/Unit

Department of Chemistry

Title

A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(III)-based i-motif probe

Abstract

An iridium(III) complex exhibiting higher responce towards i-motif DNA over dsDNA and ssDNA was employed for the construction of a TdT activity detection platform. The assay exhibited a linear signal enhancement for TdT in the concentration range of 0 to 8 U mL−1, and the limit of detection for TdT was 0.25 U mL−1.

Publication Year

2015

Journal Title

Chemical Communications

Volume number

51

Issue number

49

Publisher

Royal Society of Chemistry

First Page (page number)

9953

Last Page (page number)

9956

Referreed

1

DOI

10.1039/C5CC02790J

ISSN (print)

13597345

Link to Publisher’s Edition

http://dx.doi.org/10.1039/C5CC02790J

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