Document Type

Journal Article

Department/Unit

Department of Chemistry

Abstract

We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg2+. Unlike common DNA-based Hg2+ detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may be influenced by the distortion of dsDNA. This ‘mix-and-detect’ methodology utilized the G-quadruplex probe as the signal transducer and is simple, rapid, convenient to use and can detect down to 20 nM of Hg2+.

Publication Year

2015

Journal Title

Science and Technology of Advanced Materials

Volume number

16

Issue number

6

Publisher

National Institute for Materials Science

First Page (page number)

065004

Referreed

1

DOI

10.1088/1468-6996/16/6/065004

ISSN (print)

14686996

Link to Publisher’s Edition

http://dx.doi.org/10.1088/1468-6996/16/6/065004

Keywords

iridium(III), exonuclease III, G-quadruplex, mercury(II) ion

Included in

Chemistry Commons

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