Department of Chemistry
Rhodium complexes as therapeutic agents
The landscape of inorganic medicinal chemistry has been dominated by the investigation of platinum, and to a lesser extent ruthenium, complexes over the past few decades. Recently, complexes based on other metal centers such as rhodium have attracted attention due to their tunable chemical and biological properties as well as distinct mechanisms of action. This perspective highlights recent examples of rhodium complexes that show diverse biological activities against various targets, including enzymes and protein–protein interactions.
Royal Society of Chemistry
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Link to Publisher’s Edition
Ma, Dik Lung, Modi Wang, Zhifeng Mao, Chao Yang, Chan-Tat Ng, and Chung-Hang Leung. "Rhodium complexes as therapeutic agents." Dalton Transactions 45.7 (2016): 2762-2771.