Department of Chemistry
Utilization of G-quadruplex-forming aptamers for the construction of luminescence sensing platforms
Aptamers are nucleic acid sequences that can recognize and bind to analytes with high affinity and selectivity. Intriguingly, a number of aptamers undergo a conformational change within the G-quadruplex motif upon ligand binding. This Minireview aims to highlight interesting examples of luminescent G-quadruplex aptamer-based probes that have been developed in recent years. Various mechanisms and sensing modes are described, and the outlook and future directions of this field are also discussed.
First Page (page number)
Last Page (page number)
Link to Publisher’s Edition
aptamers, G-quadruplexes, luminescence, oligonucleotides, sensors
Ma, Dik Lung, Wanhe Wang, Zhifeng Mao, Tian-Shu Kang, Quanbin Han, Philip Wai Hong Chan, and Chung-Hang Leung. "Utilization of G-quadruplex-forming aptamers for the construction of luminescence sensing platforms." ChemPlusChem 81.1 (2017): 8-17.