Document Type

Journal Article

Department/Unit

Department of Biology

Title

In vitro estimation of exposure of Hong Kong residents to mercury and methylmercury via consumption of market fishes

Language

English

Abstract

In order to evaluate effects of exposure to mercury (tHg) and methylmercury (MeHg) of Hong Kong residents via consumption of fish, total and bioaccessible concentrations of tHg and MeHg were measured in 10 freshwater and 10 marine fishes collected from markets in Hong Kong. Concentrations of tHg and MeHg in fishes ranged from 27.2 to 311ngg-1 (median 88.9ngg-1) and ND to 116ngg-1 (median 45.0ngg-1), respectively. Concentrations of MeHg in marine fishes (64.4±28.5ngg-1) were significantly greater than those in freshwater fishes (40.3±26.0ngg-1). Bioaccessibility tHg and MeHg was predicted for edible flesh of twenty fishes by use of an in vitro gastrointestinal assay. Bioaccessibilities of tHg and MeHg ranged from 21.4 to 51.7% (mean 37.4%) and 19.5 to 59.2% (mean 43.7%), respectively. Based on total concentrations, diets of 36% of adults and 51% of children exceeded the reference dose (RfD, 100ngkg-1bodymass(bm)d-1) for MeHg, but when bioaccessibility was considered, consumption of local market fish would not result in an EDIbio exceeded the RfD of MeHg for Hong Kong adults. These contradictory results suggested that risk assessments based on total concentrations would overestimate exposure because not all of contaminants consumed are bioaccessible. Furthermore, 9% of children had EDIbio for MeHg that exceeded the RfD, which suggests that more attention should be paid to consumption of local fish on health and development of children in Hong Kong. © 2013 Elsevier B.V.

Keywords

Bioaccessible, Dietary intake, Health risks, Asia, Mercury, Sea products

Publication Date

2013

Source Publication Title

Journal of Hazardous Materials

Volume

248-249

Start Page

387

End Page

393

Publisher

Elsevier

DOI

10.1016/j.jhazmat.2012.12.060

ISSN (print)

03043894

ISSN (electronic)

18733336

This document is currently not available here.

Share

COinS