http://dx.doi.org/10.1021/jf102242m">
 

Document Type

Journal Article

Department/Unit

Department of Biology

Title

Oral bioaccessibility of polycyclic aromatic hydrocarbons (PAHs) through fish consumption, based on an in vitro digestion model

Language

English

Abstract

An in vitro gastrointestinal digestion model was used to evaluate bioaccessibility of PAHs in 20 fish species collected from Hong Kong markets. The average bioaccessibilities of PAHs were 24.3 and 31.1%, respectively, in gastric and intestinal conditions. When bioaccessibility was taken into consideration, the values of potency equivalent concentrations (PEC) decreased from 0.53 to 0.18 ng g-1 for freshwater fish and from 1.43 to 0.35 ng g-1 for marine fish. This indicated that bioaccessibility should be taken into account for health risk assessment with regard to PAH contamination in fish. The relative accumulation ratios (Rnn) of PAH congeners were significantly correlated with their physicochemical parameters and their corresponding concentrations reported in subcutaneous fats of Hong Kong residents. The data suggest that Rnn values calculated in the present study could effectively reflect the accumulations of PAHs in the human body. © 2010 American Chemical Society.

Keywords

Bioaccessibility, freshwater fish, gastrointestinal digestion model;Hong Kong, marine fish, PAHs

Publication Date

2010

Source Publication Title

Journal of Agricultural and Food Chemistry

Volume

58

Issue

21

Start Page

11517

End Page

11524

Publisher

American Chemical Society

ISSN (print)

00218561

ISSN (electronic)

15205118

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