Document Type

Journal Article

Department/Unit

Department of Biology

Title

Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticle

Language

English

Abstract

It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords

antibodies, magnetic nanoparticles, nanoparticles, regenerative medicine, stem cells

Publication Date

2013

Source Publication Title

Angewandte Chemie International Edition

Volume

52

Issue

47

Start Page

12298

End Page

12302

Publisher

Wiley-VCH Verlag

DOI

10.1002/anie.201305482

Link to Publisher's Edition

http://dx.doi.org/10.1002/anie.201305482

ISSN (print)

14337851

ISSN (electronic)

15213773

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