Document Type

Journal Article

Department/Unit

Department of Biology

Title

Translational research in nasopharyngeal carcinoma

Language

English

Abstract

Nasopharyngeal carcinoma is well known to be a viral driven malignancy. Despite high loco-regional control rate with modern radiotherapy, distant metastasis remains as a major threat to the patients highlighting the importance of effective systemic therapy. Recent advances in the understanding of tumor biology, host cell-virus interaction and genetics have paved new ways for targeted therapies. This review summarizes the recent advances into our knowledge and understanding of NPC and highlights potential novel therapeutic strategies that may prove useful to treat this disease. © 2014 Elsevier Ltd. All rights reserved.

Keywords

Angiogenesis, EBV, Growth factor receptor, NPC, Targeted therapy

Publication Date

2014

Source Publication Title

Oral Oncology

Volume

50

Issue

5

Start Page

345

End Page

352

Publisher

Elsevier

DOI

10.1016/j.oraloncology.2013.11.005

ISSN (print)

13688375

ISSN (electronic)

18790593

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