http://dx.doi.org/10.1152/physiol.00001.2014">
 

Document Type

Journal Article

Department/Unit

Department of Biology

Title

Germ cell transport across the seminiferous epithelium during spermatogenesis

Language

English

Abstract

Transport of germ cells across the seminiferous epithelium is crucial to spermatogenesis. Its disruption causes infertility. Signaling molecules, such as focal adhesion kinase, c-Yes, c-Src, and intercellular adhesion molecules 1 and 2, are involved in these events by regulating actin-based cytoskeleton via their action on actin-regulating proteins, endocytic vesicle-mediated protein trafficking, and adhesion protein complexes. We critically evaluate these findings and provide a hypothetical framework that regulates these events. © 2014 Int. Union Physiol. Sci./Am. Physiol. Soc.

Publication Date

2014

Source Publication Title

Physiology

Volume

29

Issue

4

Start Page

286

End Page

298

Publisher

American Physiological Society

ISSN (print)

15489213

ISSN (electronic)

15489221

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