http://dx.doi.org/10.1186/1749-8546-9-19">
 

Document Type

Journal Article

Authors

Kam L. Wong, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Ricky N.S. Wong, Department of Biology, Faculty of Science, Hong Kong Baptist University, Hong Kong Special Administrative RegionFollow
Liang Zhang, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Wing K. Liu, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
Tzi B. NG, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
Pang C. Shaw, School of Life Sciences and Centre for Protein Science and Crystallography, Faculty of Science, Hong Kong Special Administrative Region, The Chinese University of Hong Kong
Philip Chi L. Kwok, Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, Hong Kong Special Administrative Region, The University of Hong Kong
Yau M. Lai, Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong Special Administrative Region
Zhang J. Zhang, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Yanbo Zhang, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Yao Tong, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Ho-Pan Cheung, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Jia Lu, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Stephen Cho W. Sze, School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region

Department/Unit

Department of Biology

Title

Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Language

English

Abstract

Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo medicinalis (medicinal leech), Eisenia fetida (earthworm), and Mesobuthus martensii (Chinese scorpion), and from herbal medicines derived from species such as Cordyceps militaris, Ganoderma, Momordica cochinchinensis, Viscum album, Poria cocos, Senna obtusifolia, Panax notoginseng, Smilax glabra, Ginkgo biloba, Dioscorea batatas, and Trichosanthes kirilowii. This article reviews the isolation methods, molecular characteristics, bioactivities, pharmacological properties, and potential uses of bioactive proteins originating from these Chinese medicines. © 2014 Wong et al.; licensee BioMed Central Ltd.

Publication Date

2014

Source Publication Title

Chinese Medicine

Volume

9

Issue

19

Start Page

1

End Page

14

Publisher

BioMed Central

ISSN (print)

17498546

ISSN (electronic)

17498546

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