Department of Chemistry
Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea
Antrodia cinnamomea (AC) is an endemic mushroom species of Taiwan, and has been demonstrated to possess diverse biological and pharmacological activities, such as anti-hypertension, anti-hyperlipidemia, anti-inflammation, anti-oxidation, anti-tumor, and immunomodulation. This review focuses on the inhibitory effects of AC on hepatitis, hepatocarcinoma, and alcohol-induced liver diseases (e.g., fatty liver, fibrosis). The relevant biochemical and molecular mechanisms are addressed. Overall, this review summarizes the hepatoprotective activities in vitro and in vivo. However, there is no doubt that human and clinical trials are still limited, and further studies are required for the development of AC-related products. © 2013 Yue et al.; licensee BioMed Central Ltd.
Source Publication Title
Yue, Patrick Ying-Kit, Yi-Yi Wong, Kay Yuen-Ki Wong, Yeuk-Ki Tsoi, and Kelvin Sze-Yin Leung. "Current evidence for the hepatoprotective activities of the medicinal mushroom Antrodia cinnamomea." Chinese Medicine 8.21 (2013): 1-7.