Department of Chemistry
Nanoparticle–DNA–polymer composites for hepatocellular carcinoma cell labeling, sensing, and magnetic resonance imaging
This paper describes comparative studies and protocols in (1) self-assembling of ultrasmall superparamagnetic iron oxide nanoparticle (NP), circular plasmid DNA, and branched polyethylenimine (PEI) composites; (2) magnetofection; (3) gene delivery, (4) magnetic resonance imaging (MRI), and (5) cytotoxicity of the composites toward hepatocellular carcinoma HepG2 cells. © 2013 Elsevier Inc.
Cellular uptake, Gene delivery, Magnetic resonance imaging, Magnetofection, Nanoparticle, Self-assembly
Source Publication Title
Leung, Ken Cham-Fai, Siu-Fung Lee, Chi-Hin Wong, Chun-Pong Chak, Josie M.Y. Lai, Xiao-Ming Zhu, Yi-Xiang J. Wang, Kathy W.Y. Sham, and Christopher H.K. Cheng. "Nanoparticle–DNA–polymer composites for hepatocellular carcinoma cell labeling, sensing, and magnetic resonance imaging." Methods 64.3 (2013): 315-321.