Document Type

Journal Article

Department/Unit

Department of Chemistry

Title

Nanoparticle–DNA–polymer composites for hepatocellular carcinoma cell labeling, sensing, and magnetic resonance imaging

Language

English

Abstract

This paper describes comparative studies and protocols in (1) self-assembling of ultrasmall superparamagnetic iron oxide nanoparticle (NP), circular plasmid DNA, and branched polyethylenimine (PEI) composites; (2) magnetofection; (3) gene delivery, (4) magnetic resonance imaging (MRI), and (5) cytotoxicity of the composites toward hepatocellular carcinoma HepG2 cells. © 2013 Elsevier Inc.

Keywords

Cellular uptake, Gene delivery, Magnetic resonance imaging, Magnetofection, Nanoparticle, Self-assembly

Publication Date

2013

Source Publication Title

Methods

Volume

64

Issue

3

Start Page

315

End Page

321

Publisher

Elsevier

DOI

10.1016/j.ymeth.2013.06.006

Link to Publisher's Edition

http://dx.doi.org/10.1016/j.ymeth.2013.06.006

ISSN (print)

10462023

ISSN (electronic)

10959130

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