Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

Comparative chemical analysis of Radix Astragali and Radix Hedysari by HPLC

Language

English

Abstract

Radix Astragali and Radix Hedysari, two famous traditional Chinese medicines (TCM), were considered to possess the same efficacy in TCM traditionally. However, modern pharmacological and phytochemical investigations showed that they were different in efficacy and chemical constituents to some degree. In this study, the principal constituents of the two drugs, isoflavonoids and saponins, were comparatively analysed using HPLC-UV and HPLC-ELSD methods. The results showed that there were some common compounds, especially flavonoids, in both drugs, while the differences in the types and contents of their chemical constituents, especially in saponins, were also obvious. The similarities and differences of the chemicals may be responsible, at least partially, for the similarities and differences in their efficacies or bioactivities. © 2012 Copyright Taylor and Francis Group, LLC.

Keywords

Astragalus membranaceus, Astragalus membranaceus var. mongholicus, Hedysarum polybotrys, HPLC, Radix Astragali, Radix Hedysari

Publication Date

2012

Source Publication Title

Natural Product Research

Volume

26

Issue

20

Start Page

1935

End Page

1938

Publisher

Taylor & Francis

DOI

10.1080/14786419.2011.619188

ISSN (print)

14786419

ISSN (electronic)

14786427

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