Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

Quantitative comparison of ginsenosides and polyacetylenes in wild and cultivated American ginseng

Language

English

Abstract

Quantitative comparison of seven ginsenosides in wild and cultivated American ginseng revealed that the Rg1/Rd ratio presented a significantly large difference between cultivated and type-I (one of the defined chemotypes) wild American ginseng, facilitating this ratio as a characteristic marker for differentiating these two groups. Similarly, the ratio (Rg 1 + Re)/Rd, and the ratio of protopanaxatriol (PPT)-type ginsenosides to protopanaxadiol (PPD)-type ginsenosides showed a large difference between these two groups. On the other hand, type-II wild samples were found to have high Rg1/Rb1 and Rg1/Re ratios and low panaxydol/panaxynol ratio, which is entirely different from Type-I American ginseng, but is very similar to that of Asian ginseng. This not only suggests that the chemotype should be taken into consideration properly when using these parameters for differentiating American and Asian ginseng, but also indicates that type-II wild American ginseng may have distinct pharmacological activities and therapeutic effects. © 2010 Verlag Helvetica Chimica Acta AG.

Publication Date

2010

Source Publication Title

Chemistry and Biodiversity

Volume

7

Issue

4

Start Page

975

End Page

983

Publisher

Wiley

DOI

10.1002/cbdv.200900264

Link to Publisher's Edition

http://dx.doi.org/10.1002/cbdv.200900264

ISSN (print)

16121872

ISSN (electronic)

16121880

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