School of Chinese Medicine
Comparison of the immunoregulatory function of different constituents in Radix Astragali and Radix Hedysari
Radix Astragali (RA), known as Huangqi in China, is one of the most popular herbal medicines known worldwide to reinforce Qi. RA is traditionally prepared from the dried roots of Astragalus membranaceus (MJHQ) and A. membranaceus var. mongholicus (MGHQ). Radix Hedysari is named Hongqi (HQ), which is similar to RA. We assessed and compared the chemical constituents and bioactivity of RA and HQ. Different constituents were extracted into five major parts and were analyzed using different methods. Comparison of the immunological effects of extracts was done by using two immunological models. Results showed that flavonoids and saponins present in RA and HQ were not only structurally significantly different but also different in their immunological effect. Amino acids extract (AE) in MGHQ shows immunological effect while AE in MJHQ and HQ did not. Polysaccharides comprised the major constituents in RA and HQ. All polysaccharides extract (PE) of the three herbs showed similar levels of immunological effect in both immunological assays. © 2010 Jing Liu et al.
Source Publication Title
Journal of Biomedicine and Biotechnology
Hindawi Publishing Corporation
Link to Publisher's Edition
Chen, Hubiao, Jing Liu, Xuguang Hu, Quan Yang, Zhiling Yu, Zhongzhen Zhao, and Tao Yi. "Comparison of the immunoregulatory function of different constituents in Radix Astragali and Radix Hedysari." Journal of Biomedicine and Biotechnology 2010 (2010): 479426-1-479426-12.