Document Type

Conference Paper

Department/Unit

Department of Biology

Title

Investigation of N-methyl-D-aspartate induced mechanical behavior of neuroblastoma cells using atomic force microscopy

Language

English

Abstract

Physiological conditions of biological samples are regulated by many different parameters including mechanical and biochemical factors etc. Single-cell studies of these parameters are challenging by using conventional bioanalysis methods. However, with the recent advancement in nanotechnology, single-molecule and single-cell analysis is much more accessible. Understanding the changes of neuroblastoma cells in different mechanisms is critical for fundamental research in neurosciences. Here, we investigate the mechanical behavior of SH-SY5Y cells using atomic force microscopy. Topographic imaging of the cells and real-time quantitative analysis of their mechanical properties will be presented in the paper. © 2013 IEEE.

Publication Date

2013

Source Publication Title

Proceedings of the 13th IEEE International Conference on Nanotechnology

Start Page

329

End Page

332

Conference Location

Beijing, China

Publisher

IEEE

DOI

10.1109/NANO.2013.6720884

Link to Publisher's Edition

http://dx.doi.org/10.1109/NANO.2013.6720884

ISBN (print)

9781479906758

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