Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

Characterization of flavonoids in the ethomedicine fordiae cauliflorae radix and its adulterant millettiae pulchrae radix by HPLC-DAD-ESI-IT-TOF-MSn

Language

English

Abstract

Fordiae Cauliflorae Radix (FC, the root of Fordia cauliflora Hemsl) and Millettiae Pulchrae Radix [MP, the root of Millettia pulchra (Benth.) Kurz var. laxior (Dunn) Z. Wei], which go under the same local name of "Daluosan", have long been used in Southern China for the treatment of stroke, paralysis, dementia in children, Alzheimer's disease and other diseases. The same local name and similar functions always confuse users. To further utilize these two ethnodrugs and identify them unambiguously, an HPLC-DAD-ESI-IT-TOF-MSn method was developed to separate and characterize the flavonoids in FC and MP. A total of 41 flavonoids were detected, of which six compounds were identified by comparing their retention time and MS data with those of the reference standards, and the others were tentatively identified based on their tandem mass spectrometry data obtained in the positive ion detection mode. Nineteen of these characterized compounds are reported from these two plants for the first time. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Keywords

Ethnomedicine, Flavonoids, Fordia cauliflora, HPLC-DAD-ESI-IT-TOF-MSn, Identification, Millettia pulchra var. laxior

Publication Date

2013

Source Publication Title

Molecules

Volume

18

Issue

12

Start Page

15134

End Page

15152

Publisher

MDPI

DOI

10.3390/molecules181215134

Link to Publisher's Edition

http://dx.doi.org/10.3390/molecules181215134

ISSN (print)

14203049

ISSN (electronic)

14203049

This document is currently not available here.

Share

COinS