http://dx.doi.org/10.1016/j.tifs.2014.09.002">
 

Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

An insight into anti-inflammatory effects of fungal beta-glucans

Language

English

Abstract

© 2014 Elsevier Ltd.β-Glucans from fungi exhibit a broad spectrum of biological activities including anti-tumor, immune-modulating and anti-inflammatory properties. The anti-inflammatory effect is mediated through the regulation of various inflammatory cytokines, such as nitric oxide (NO), interleukins (ILs), tumor necrosis factor alpha (TNF)-α, interferon gamma (INF)-γ as well as non-cytokine mediator, prostaglandin E2 (PGE2). Up to now, the anti-inflammatory activity of β-glucans has received little attention. It is worthwhile to investigate the anti-inflammatory properties of fungal β-glucans in a separate review, discussing invitro studies, animal studies and human studies on anti-inflammation effects of fungal β-glucans, as well as the structure-anti-inflammatory activity relationships.

Publication Date

2015

Source Publication Title

Trends in Food Science and Technology

Volume

41

Issue

1

Start Page

49

End Page

59

Publisher

Elsevier

ISSN (print)

09242244

ISSN (electronic)

18793053

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