School of Chinese Medicine
Hemiterpene glucosides with anti-platelet aggregation activities from ilex pubescens
Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities. © 2005 American Chemical Society and American Society of Pharmacognosy.
Source Publication Title
Journal of Natural Products
American Chemical Society
Jiang, Zhi-Hong, Jing-Rong Wang, Min Li, Zhong-Qiu Liu, Ka-Yee Chau, Chi Zhao, and Liang Liu. "Hemiterpene glucosides with anti-platelet aggregation activities from ilex pubescens." Journal of Natural Products 68.3 (2005): 397-399.