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Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Title

Hemiterpene glucosides with anti-platelet aggregation activities from ilex pubescens

Language

English

Abstract

Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities. © 2005 American Chemical Society and American Society of Pharmacognosy.

Publication Date

2005

Source Publication Title

Journal of Natural Products

Volume

68

Issue

3

Start Page

397

End Page

399

Publisher

American Chemical Society

ISSN (print)

01633864

ISSN (electronic)

15206025

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