Department of Chemistry
A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb3+,Er3+ nanocrystals for in vitro cell imaging
Hexagonal-phase NaYF4:Yb3+,Er3+ up-conversion nanocrystals (UCNCs) are synthesized by a combination of refluxing and hydrothermal treatment. This strategy leads to only a slight increase in particle size, from 4.5 to ca. 10 nm, during the cubic-to-hexagonal phase transition. The hexagonal UCNCs can be internalized by HeLa cells and exhibit visible emission in the cells under near-infrared excitation. © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
biosensors, fluorescent probes, imaging, lanthanide nanocrystals, phase transitions
Source Publication Title
Wang, Zhen-Ling, Jianhua Hao, Helen L. W. Chan, Wing-Tak Wong, and Ka-Leung Wong. "A strategy for simultaneously realizing the cubic-to-hexagonal phase transition and controlling the small size of NaYF4:Yb3+,Er3+ nanocrystals for in vitro cell imaging." Small 8.12 (2012): 1863-1868.