Department of Physics
Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy
An enhanced photosensitizer combining biocompatible CdSe quantum dots (QDs) with water-soluble porphyrin was synthesized by a facile method. The two photon absorption (TPA) cross-section values of the QDs range from 800 to 2400 Goeppert-Mayer units (GM), depending on the excitation wavelength, calculated by the standard method using R6G as a reference. The singlet oxygen generation under two-photon excitation (TPE) in the QD-porphyrin system was two times greater than that in the porphyrin solution alone. This study underlines the potential of QD-based photosensitizers for biological applications in TPE photodynamic therapy. © 2011 The Royal Society of Chemistry.
Source Publication Title
Journal of Materials Chemistry
Royal Society of Chemistry
Qi, Zu-De, Dong-Wei Li, Peng Jiang, Feng-Lei Jiang, Yue-Sheng Li, Yi Liu, Wai-Kwok Wong, and Kok-Wai Cheah. "Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy." Journal of Materials Chemistry 21.8 (2011): 2455-2458.