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Document Type

Journal Article

Department/Unit

Department of Chemistry

Title

A 2,7-carbazole-based dicationic salt for fluorescence detection of nucleic acids and two-photon fluorescence imaging of RNA in nucleoli and cytoplasm

Language

English

Abstract

A new carbazole-derived dicationic compound, namely 2,7-bis(1-hydroxyethyl- 4-vinylpyridinium iodine)-N-ethylcarbazole (2,7-9E-BHVC), with a large two-photon action absorption cross section in nucleic acids has been obtained. Moreover, it possesses the potential of imaging RNA in nucleoli and cytoplasm in two-photon fluorescence microscopy and exhibits good counterstain compatibility with the commercial fluorescent nucleic dye DAPI. © 2011 The Royal Society of Chemistry.

Publication Date

2011

Source Publication Title

Organic and Biomolecular Chemistry

Volume

9

Issue

10

Start Page

3615

End Page

3618

Publisher

Royal Society of Chemistry

ISSN (print)

14770520

ISSN (electronic)

14770539

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