Department of Chemistry
Luminescent ruthenium(II) complex bearing bipyridine and N-heterocyclic carbene-based C^N^C pincer ligand for live-cell imaging of endocytosis
© 2015, Nature Publishing Group. All rights reserved. Luminescent ruthenium(II)-cyanide complex with N-heterocyclic carbene pincer ligand C∧N∧C = 2,6-bis(1-butylimidazol-2-ylidene)pyridine and 2,2′-bipyridine (bpy) shows minimal cytotoxicity to both human breast carcinoma cell (MCF-7) and human retinal pigmented epithelium cell (RPE) in a wide range of concentration (0.1-500 μM), and can be used for the luminescent imaging of endocytosis of the complex in these cells.
Source Publication Title
Nature Publishing Group
Tsui, Wai-Kuen, Lai-Hon Chung, Matthew Man-Kin Wong, Wai-Him Tsang, Hoi-Shing Lo, Yaxiang Liu, Chung-Hang Leung, Dik-Lung Ma, Sung-Kay Chiu, and Chun-Yuen Wong. "Luminescent ruthenium(II) complex bearing bipyridine and N-heterocyclic carbene-based C^N^C pincer ligand for live-cell imaging of endocytosis." Scientific Reports 5 (2015): 9070.