Department of Chemistry
Practical synthetic approach to chiral sulfonimides (CSIs) – chiral Brønsted acids for organocatalysis
A general approach to the synthesis of optically pure 3,3'diaryl chiral sulfonimides (CSIs) from racemic BINOL has been developed. ortho-Lithiation is directed by the sulfonyl groups, and the resulting dihalides serve as the common precursors for the aryl-substituted CSIs. © 2010 Wiley-VCH Verlag GmbH &, Co. KGaA, Weinheim.
Bransted acids, Chirality, Organocatalysis, Sulfonimides
Source Publication Title
European Journal of Inorganic Chemistry
He, Hao, Ling-Yan Chen, Wai-Yeung Wong, Wing-Hong Chan, and Albert W. M. Lee. "Practical synthetic approach to chiral sulfonimides (CSIs) – chiral Brønsted acids for organocatalysis." European Journal of Inorganic Chemistry 2010.22 (2010): 4181-4184.