Department of Chemistry
Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water
An air-stable organoantimony complex with a 5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine framework was synthesized, characterized, and found to exhibit high catalytic efficiency towards one-pot Mannich reaction with high diastereoselectivity in water. The catalyst can be recycled 10 times without showing any appreciable loss of efficiency. This catalytic system affords a simple and efficient approach for the synthesis of β-amino ketones. © 2010 Elsevier B.V. All rights reserved.
Catalyst, Diastereoselectivity, Direct Mannich reaction, Lewis acid, Organoantimony
Source Publication Title
Journal of Organometallic Chemistry
Xia, Jun, Renhua Qiu, Shuangfeng Yin, Xiaowen Zhang, Shenglian Luo, Chak-Tong Au, Kai Xia, and Wai-Yeung Wong. "Synthesis and structure of an air-stable organoantimony complex and its use as a catalyst for direct diastereoselective Mannich reactions in water." Journal of Organometallic Chemistry 695.11-10 (2010): 1487-1492.