Department of Chemistry
A novel ratiometric emission probe for Ca2+ in living cells
A ratiometric fluorescent probe for Ca2+ based on 1,3,4-oxadiazole derivative has been designed and developed. The probe exhibits a large Stokes shift of 202 nm and a highly selective ratiometric emission response (490/582 nm) to Ca2+ over other metal cations. Additionally, the probe can readily reveal the changes of intracellular Ca2+ concentration in living human umbilical vein endothelial cells. © The Royal Society of Chemistry 2013.
Source Publication Title
Organic and Biomolecular Chemistry
Royal Society of Chemistry
Liu, Qiaoling, Wei Bian, Heping Shi, Li Fan, Shaomin Shuang, Chuan Dong, and Martin M. F. Choi. "A novel ratiometric emission probe for Ca2+ in living cells." Organic and Biomolecular Chemistry 11.3 (2013): 503-508.