Department of Chemistry
A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy
An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (ΦΔ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation. © 2012 The Royal Society of Chemistry.
Source Publication Title
Royal Society of Chemistry
Zhang, Jing-Xiang, Hongguang Li, Chi-Fai Chan, Rongfeng Lan, Wai-Lun Chan, Ga-Lai Law, Wai-Kwok Wong, and Ka-Leung Wong. "A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy." Chemical Communications 48.77 (2012): 9646-9648.