Department of Chemistry
Enhanced cellular uptake and gene delivery of glioblastoma with deferoxamine-coated nanoparticle/plasmid DNA/branched polyethylenimine composites
Ternary composite nanomaterials based on deferoxamine-coated superparamagnetic iron oxide nanoparticles (8-10 nm), circular plasmid DNA (∼4 kb) with fluorescent/luminescent reporter group, and branched polyethylenimine (25 kDa, PDI = 2.5) were prepared and compared in terms of their efficiencies in transfecting brain tumor cells at low concentration. © 2013 The Royal Society of Chemistry.
Source Publication Title
Royal Society of Chemistry
Leung, Ken Cham-Fai, Chun-Pong Chak, Siu-Fung Lee, Josie M.Y. Lai, Xiao-Ming Zhu, Yi-Xiang J. Wang, Kathy W. Y. Sham, and Christopher H.K. Cheng. "Enhanced cellular uptake and gene delivery of glioblastoma with deferoxamine-coated nanoparticle/plasmid DNA/branched polyethylenimine composites." Chemical Communications 49.6 (2013): 549-551.