Document Type

Journal Article

Department/Unit

School of Chinese Medicine

Language

English

Abstract

Objectives: It was the aim of this study to determine whether (1) Parkinson's disease (PD) patients can be divided into different traditional Chinese medicine (TCM) constitutions based on the 44-item Traditional Chinese Medical Constitutional Scale and Classification (TCM-CSC, Chinese version, 中醫體質及分型量表), (2) whether levodopa usage correlates with the TCM classification type, and (3) whether there is a difference in the mean daily intake of levodopa between males and females in any of the constitutional types. Methods: PD patients who had visited the TCM clinic of the Hong Kong Baptist University (HKBU) or who had attended the PD public talks organized by HKBU and the Association of Parkinson's Disease in Hong Kong were invited for interviews with TCM assessors. The TCM-CSC (Chinese version) was used in the assessment to divide patients into four different constitutions: the balanced constitution (type A), the yang-deficiency constitution (type B), the yin-deficiency constitution (type C) and the stasis constitution (type D). Results: Sixty-three patients (29 males, 34 females; mean age 63.65 ± 8.116 years; mean PD duration 5.49 ± 4.544 years) participated in the study. Sixteen PD patients (26%) had only one type of TCM constitution, while 47 PD patients (74%) had more than one type of TCM constitution. Type D patients showed the lowest intake of daily levodopa. There was no significant difference in the mean daily intake of levodopa between males and females in any of the constitutional types. Conclusions: (1) PD patients cannot be divided into different constitutional types based on the TCM-CSC effectively. (2) In general, levodopa usage does not correlate with the constitutional type; however, patients with the stasis constitution (type D) showed the lowest levodopa intake compared to the other constitutions. (3) There was no significant difference in the mean daily intake of levodopa between males and females. Further research on the treatment pattern of different TCM constitutions, using large samples, is warranted.

Keywords

Parkinsonߣs disease, Constitutions, Traditional Chinese medicine, Pattern differentiation, Levodopa

Publication Date

4-2015

Source Publication Title

Integrative Medicine International

Volume

1

Issue

3

Start Page

170

End Page

175

Publisher

Kager

Peer Reviewed

1

Copyright

This is an Open Access article licensed under the terms of the Creative Commons AttributionNonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only

Funder

This work was supported by research grants (HMRF12132091, IRMS/12-13/1A), Mr. and Mrs. Ko Chi Ming Center for Parkinson's Disease Research from HKBU and the Dr. Ho Tzu-leung Foundation.

DOI

10.1159/000369530

Link to Publisher's Edition

http://dx.doi.org/10.1159/000369530

ISSN (electronic)

22967362

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