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Document Type

Journal Article

Department/Unit

Department of Chemistry

Title

Simple DNA-based logic gates responding to biomolecules and metal ions'

Language

English

Abstract

The combination of chemical and molecular technologies to emulate silicon-based processing has arisen as a fascinating area of research in the scientific community. This has stimulated the development of molecular-scale logic gates that can parallel the Boolean functions representing the fundamental basis of modern computing. In this regard, the extraordinary diversity of nucleic acid structures and functions can be potentially harnessed to perform logic operations for molecular computers. In this Perspective, we highlight recent advances in the development of simple DNA logic gates devices producing luminescence, colorimetric, electrochemical or electrochemiluminescence signals responding to biomolecules and metal ions for sensory and computing applications. © 2013 The Royal Society of Chemistry.

Publication Date

2013

Source Publication Title

Chemical Science

Volume

4

Issue

9

Start Page

3366

End Page

3380

Publisher

Royal Society of Chemistry

ISSN (print)

20416520

ISSN (electronic)

20416539

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