Department of Chemistry
Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin
A water-soluble europium(III) complex (1) has been synthesized and demonstrated to be a specific fluorescence probe for the paralytic shellfish toxin saxitoxin, a neurotoxin that blocks the voltage-gated sodium channels on cell membranes. Saxitoxin binds to the europium complex (KB= 6.1×104M-1) and triggers a two-photon induced f-f emission enhancement by over 100% and increases the two-photon absorption crosssection from 9 to 36 GM. © 2011 American Chemical Society.
Source Publication Title
American Chemical Society
He, Shuzhong, Hongguang Li, Yuk-Wang Yip, Chi-Tung Yeung, Yuen On Fung, Hoi-Kuan Kong, Ho-Lun Yeung, Ga-Lai Law, Ka-Leung Wong, Chi-Sing Lee, Michael Hon-Wah Lam, Margaret B. Murphy, Paul Kwan-Sing Lam, and Wing-Tak Wong. "Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin." Organic Letters 13.19 (2011): 5036-5039.