Document Type

Journal Article

Department/Unit

Department of Chemistry

Title

Review of biological and pharmacological activities of the endemic taiwanese bitter medicinal mushroom, antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (higher basidiomycetes)

Language

English

Abstract

Antrodia camphorata is an extremely rare fungus native to the forested regions of Taiwan. It is also a traditional Chinese medicine, and Taiwanese aborigines applied it for treating liver diseases and protecting from food and drug intoxication. Scientific studies have demonstrated that A. camphorata crude extracts and pure compounds possess a variety of beneficial functions, such as anti-hypertensive, anti-hyperlipidemic, anti-inflammatory, antioxidant, anti-tumor, and immuno-modulatory activities. Recent studies have shown that many of these biological and pharmacological activities can be attributed to various active constituents, including polysaccharides, terpenoids, steroids, lignans, benzoquinone derivatives, benzenoids, and maleic and succinic acid derivatives. A. camphorata has been considered as a novel phytotherapeutic agent. However, detailed mechanistic studies or even clinical trials on A. camphorata are still rare. With the help of modern analytical techniques, it is not surprising that many novel constituents are being identified or fractionated from A. camphorata mycelium and fruiting bodies. This review summarizes the latest published results from A. camphorata research, focusing on the biological and pharmacological activities of the crude extract and known constituents of A. camphorata. © 2012 Begell House, Inc.

Keywords

Anti-hypertensive, Anti-inflammatory, Anti-oxidant, Anti-tumor, Antrodia camphorata, Dietary supplements, Hepatoprotection, Immuno-modulatory activities, Medicinal mushrooms, Medicinal value

Publication Date

2012

Source Publication Title

International Journal of Medicinal Mushrooms

Volume

14

Issue

3

Start Page

241

End Page

256

Publisher

Begell House

DOI

10.1615/IntJMedMushr.v14.i3.20

ISSN (print)

15219437

ISSN (electronic)

19404344

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