Recent developments in G-auadruplex probes
Department of Chemistry
Accumulating evidence has linked G-quadruplex structures to a number of biological processes in vivo, including DNA replication, transcription, and genomic maintenance. However, the precise function and mechanism of G-quadruplex formation in mammalian cells remains poorly defined. Therefore, the development of small-molecule G-quadruplex probes has attracted significant attention in recent years. This review highlights examples of G-quadruplex probes that have been reported over the last few years, some of which have been employed for cellular imaging or for use in the construction of G-quadruplex-based analytical sensing platforms.
Source Publication Title
Chemistry and Biology
Link to Publisher's Edition
Ma, D., Zhang, Z., Wang, M., Lu, L., Zhong, H., & Leung, C. (2015). Recent developments in G-auadruplex probes. Chemistry and Biology, 22 (7). https://doi.org/10.1016/j.chembiol.2015.06.016