Document Type

Journal Article

Department/Unit

Department of Chemistry

Language

English

Abstract

We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg2+. Unlike common DNA-based Hg2+ detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may be influenced by the distortion of dsDNA. This ‘mix-and-detect’ methodology utilized the G-quadruplex probe as the signal transducer and is simple, rapid, convenient to use and can detect down to 20 nM of Hg2+.

Keywords

iridium(III), exonuclease III, G-quadruplex, mercury(II) ion

Publication Date

2015

Source Publication Title

Science and Technology of Advanced Materials

Volume

16

Issue

6

Start Page

065004

Publisher

National Institute for Materials Science

Peer Reviewed

1

DOI

10.1088/1468-6996/16/6/065004

Link to Publisher's Edition

http://dx.doi.org/10.1088/1468-6996/16/6/065004

ISSN (print)

14686996

Included in

Chemistry Commons

Share

COinS