Document Type

Journal Article

Title

Utilization of G-quadruplex-forming aptamers for the construction of luminescence sensing platforms

Department/Unit

Department of Chemistry

Language

English

Abstract

Aptamers are nucleic acid sequences that can recognize and bind to analytes with high affinity and selectivity. Intriguingly, a number of aptamers undergo a conformational change within the G-quadruplex motif upon ligand binding. This Minireview aims to highlight interesting examples of luminescent G-quadruplex aptamer-based probes that have been developed in recent years. Various mechanisms and sensing modes are described, and the outlook and future directions of this field are also discussed.

Keywords

aptamers, G-quadruplexes, luminescence, oligonucleotides, sensors

Publication Date

2017

Source Publication Title

ChemPlusChem

Volume

81

Issue

1

Start Page

8

End Page

17

Publisher

Wiley-VCH Verlag

Peer Reviewed

1

DOI

10.1002/cplu.201600036

Link to Publisher's Edition

http://dx.doi.org/10.1002/cplu.201600036

ISSN (electronic)

21926506

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