Document Type

Journal Article

Department/Unit

Department of Chemistry

Language

English

Abstract

Fonsecin B has been identified as stabilizing ligand of c-mycG-quadruplexDNA using high-throughput virtual screening of a natural product database, and inhibited Taq polymerase-mediated DNA extension in vitro through stabilization of the G-quadruplex secondary structure.

Publication Date

2010

Source Publication Title

Chemical Communications

Volume

46

Issue

26

Start Page

4680

End Page

4682

Publisher

Royal Society of Chemistry

Peer Reviewed

1

DOI

10.1039/B926359D

Link to Publisher's Edition

http://dx.doi.org/10.1039/B926359D

ISSN (print)

1359-7345

Included in

Chemistry Commons

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