Year of Award
Doctor of Philosophy (PhD)
Department of Chemistry.
Photochemotherapy;Rare earth metals;Analysis
1.2\xPrior to the PDT, we have also synthesized a series of water-soluble homoleptic lanthanides (Ln3+ = Gd, Er, and Yb) sandwich (DD) di-PEGylated porphyrin complexes. The Yb complex (YbDD) has shown the same NIR emission quantum yield as the highest record Yb complex in the literature (Yb-RhB), yet, the emission intensity is double compared to the Yb-N. This implies a new thinking about the quantity measurement for biological imaging. The brightness might be the prime factor for the development of luminescence in vitro/in vivo imaging agent rather than the emission quantum yield.
Includes bibliographical references.
Zhou, Yan, "Synthesis, photophysical and biological studies of lanthanide complexes for photodynamic therapy" (2017). Open Access Theses and Dissertations. 467.
Available for download on Monday, April 06, 2020