Department of Mathematics
Silent aspiration and swallowing physiology after radiotherapy in patients with nasopharyngeal carcinoma
Background. There is a paucity of knowledge on dysphagia in patients with nasopharyngeal carcinoma postradiotherapy (NPC post-RT). The purpose of this study was to establish silent aspiration occurrence, safe bolus consistency, and their relationship with swallowing physiology in patients with dysphagic NPC post-RT. Methods. Eighty-five patients with dysphagic NPC post-RT were assessed across 4 bolus consistencies. We compared penetration-aspiration scores against 4 swallowing physiology impairments. Results. Silent aspiration occurred in 65.9% of patients with dysphagia, with 64.7% on thin fluids, 35.3% on thick fluids, 11.8% on pureed diet, and 5.9% on soft diet. Multivariate analysis of variance (MANOVA) indicated pharyngeal contraction and swallowing response had significant effect on thick fluids (p =.002), thin fluids (p =.017), and soft diet (p =.031). Conclusion. Silent aspiration of thin fluids is a common occurrence in dysphagic NPC post-RT, with least aspiration noted on soft diet. Considering the high incidence of silent aspiration, instrumental assessment in this cohort is crucial. © 2010 Wiley Periodicals, Inc. Head Neck, 2010 Copyright © 2010 Wiley Periodicals, Inc.
bolus consistency, dysphagia, nasopharyngeal carcinoma, penetration-aspiration, swallowing physiology
Source Publication Title
Head and Neck
Link to Publisher's Edition
Ng, L., Lee, K., Chiu, S., Ku, P., Van Hasselt, C., & Tong, M. (2011). Silent aspiration and swallowing physiology after radiotherapy in patients with nasopharyngeal carcinoma. Head and Neck, 33 (9), 1335-1339. https://doi.org/10.1002/hed.21627