Department of Biology
Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticle
It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
antibodies, magnetic nanoparticles, nanoparticles, regenerative medicine, stem cells
Source Publication Title
Angewandte Chemie International Edition
Link to Publisher's Edition
Lui, C., Tsui, Y., Ho, A., Shum, D., Chan, Y., Wu, C., Li, H., Tsang, S., & Yung, K. (2013). Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticle. Angewandte Chemie International Edition, 52 (47), 12298-12302. https://doi.org/10.1002/anie.201305482