Department of Biology
Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticle
It stems from the magnetism: The extraction of stem/progenitor cells from the brain of live animals is possible using antibodies conjugated to magnetic nanoparticles (Ab-MNPs). The Ab-MNPs are introduced to a rat's brain with a superfine micro-syringe. The stem cells attach to the Ab-MNPs and are magnetically isolated and removed. They can develop into neurospheres and differentiate into different types of cells outside the subject body. The rat remains alive and healthy. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
antibodies, magnetic nanoparticles, nanoparticles, regenerative medicine, stem cells
Source Publication Title
Angewandte Chemie International Edition
Link to Publisher's Edition
Lui, C. N P, Y. P. Tsui, A. S L Ho, D. K Y Shum, Y. S. Chan, C. T. Wu, H. W. Li, S. C. Edman Tsang, and K. K L Yung. "Neural stem cells harvested from live brains by antibody-conjugated magnetic nanoparticle." Angewandte Chemie International Edition 52.47 (2013): 12298-12302.