Department of Chemistry
A coumarin-based fluorescent chemosensor CAQA has been synthesized. It can selectively and sensitively recognize Cu2+ in aqueous acetonitrile solutions. Using the Cu-containing complex CAQA-Cu2+ as a sensing ensemble, the device demonstrates highly selective recognition of His/biothiols and was applied in fluorescence imaging of histidine in hard-to-transfect living cells.
Source Publication Title
Royal Society of Chemistry
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Link to Publisher's Edition
You, Qi-Hua, Albert Wai-Ming Lee, Wing-Hong Chan, Xiao-Ming Zhu, and Ken Cham-Fai Leung. "A coumarin-based fluorescent probe for recognition of Cu2+ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach." Chemical Communications 50.47 (2014): 6207-6210.