Document Type
Journal Article
Department/Unit
Department of Chemistry
Title
Ionic-liquid-based dispersive liquid–liquid microextraction for high-throughput multiple food contaminant screening
Language
English
Abstract
This paper describes an innovation of dispersive liquid-liquid microextraction enabling multiple-component analysis of eight high-priority food contaminants in two chemically distinctive families: Sudan dyes and phthalate plasticizers. To provide convenient sample handling for solid and solid-containing matrices, a modified dispersive liquid-liquid microextraction procedure used an extractant precoated frit to perform simultaneous filtration, solvent mixing, and phase dispersion in one simple step. A binary ionic liquid extractant system was carefully tuned to deliver high quality analysis based only on affordable LC with diode array detector instrumentation. The method is comprehensively validated for robust quantification with good precision (6.9-9.8% RSD) in a linear 2-1000 μg/L range. Having accomplished enrichment factors up to 451, the treatment enables sensitive detection at 0.09-1.01 μg/L levels. Analysis of six high-risk solid condiments and sauces further verified its practical applicability within a 70-120% recovery range. Compared to other approaches, the current dispersive liquid-liquid microextraction treatment offers major advantages in terms of minimal solvent (1.5 mL) and sample (0.1 g) consumption, ultra-high analytical throughput (6 min), and the ability to handle complex solid matrices. The idea of performing simultaneous analysis for multiple contaminants presented here fosters a more effective mode of operation in food control routines. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Keywords
Dispersive liquid-liquid microextraction, Food control, Ionic liquids, Phthalates, Sudan dyes
Publication Date
2013
Source Publication Title
Journal of Separation Science
Volume
36
Issue
23
Start Page
3791
End Page
3798
Publisher
Wiley-VCH Verlag
DOI
10.1002/jssc.201300807
Link to Publisher's Edition
ISSN (print)
16159306
ISSN (electronic)
16159314
Recommended Citation
Ho, Yee-Man, Yeuk-Ki Tsoi, and Kelvin Sze-Yin Leung. "Ionic-liquid-based dispersive liquid–liquid microextraction for high-throughput multiple food contaminant screening." Journal of Separation Science 36.23 (2013): 3791-3798.