Department of Chemistry
Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel–Crafts reaction of homoallylic alcohols
An efficient synthetic method to prepare highly substituted indenes in moderate to excellent yields that relies on Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols under mild conditions is described.
Brønsted acid, Friedel-Crafts reaction, Homoallylic alcohols, Homogeneous catalysis, Indene derivatives
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Zhang, X., Teo, W., Rao, W., Ma, D., Leung, C., & Chan, P. (2014). Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel–Crafts reaction of homoallylic alcohols. Tetrahedron Letters, 55 (29), 3881-3884. https://doi.org/10.1016/j.tetlet.2014.05.027