School of Chinese Medicine
Protopanaxatriol-type ginsenosides from the root of Panax ginseng
Ginseng, the root of Panax ginseng C. A. Meyer (Araliaceae), is one of the most important traditional medicines and functional foods. A detailed phytochemical investigation on the roots of P. ginseng led to the isolation of 6 new natural protopanaxatriol (PPT)-type ginsenosides, ginsenosides Re 1-Re6 (compounds 1-6), along with 10 known PPT-type ginsenosides. Their structures were elucidated on the basis of chemical and spectroscopic analyses, including high-resolution mass spectrometry (HRMS) and 1D and 2D nuclear magnetic resonance (NMR). The unusual α-d- glucopyranosyl-(1→3)-β-d-glucopyranosyl sugar chain, as found in compounds 1 and 2, is reported in the genus Panax for the first time. © 2010 American Chemical Society.
Araliaceae, ginsenoside, ginsenosides Re1-Re6, Panax ginseng, protopanaxatriol
Source Publication Title
Journal of Agricultural and Food Chemistry
American Chemical Society
Link to Publisher's Edition
Zhu, Guo-Yuan, Ying-Wei Li, Desmond Kwok-Po Hau, Zhi-Hong Jiang, Zhi-Ling Yu, and Wang-Fun Fong. "Protopanaxatriol-type ginsenosides from the root of Panax ginseng." Journal of Agricultural and Food Chemistry 59.1 (2011): 200-205.