School of Chinese Medicine
Hemiterpene glucosides with anti-platelet aggregation activities from ilex pubescens
Two new hemiterpene glucosides named pubescenosides A and B were isolated from the root of Ilex pubescens. Their structures were elucidated on the basis of spectroscopic and chemical evidence as 2-(trans-caffeoyloxy)methyl-3-hydroxy- 1-butene-4-O-β-D-glucopyranoside and 2-hydroxymethyl-3-caffeoyloxy-1- butene-4-O-β-D-glucopyranoside, respectively. Pharmacological investigation on pubescenosides A and B indicated that both possess potent anti-platelet aggregation activities. © 2005 American Chemical Society and American Society of Pharmacognosy.
Source Publication Title
Journal of Natural Products
American Chemical Society
Link to Publisher's Edition
Jiang, Z., Wang, J., Li, M., Liu, Z., Chau, K., Zhao, C., & Liu, L. (2005). Hemiterpene glucosides with anti-platelet aggregation activities from ilex pubescens. Journal of Natural Products, 68 (3), 397-399. https://doi.org/10.1021/np049735y