Department of Physics
Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy
An enhanced photosensitizer combining biocompatible CdSe quantum dots (QDs) with water-soluble porphyrin was synthesized by a facile method. The two photon absorption (TPA) cross-section values of the QDs range from 800 to 2400 Goeppert-Mayer units (GM), depending on the excitation wavelength, calculated by the standard method using R6G as a reference. The singlet oxygen generation under two-photon excitation (TPE) in the QD-porphyrin system was two times greater than that in the porphyrin solution alone. This study underlines the potential of QD-based photosensitizers for biological applications in TPE photodynamic therapy. © 2011 The Royal Society of Chemistry.
Source Publication Title
Journal of Materials Chemistry
Royal Society of Chemistry
Link to Publisher's Edition
Qi, Z., Li, D., Jiang, P., Jiang, F., Li, Y., Liu, Y., Wong, W., & Cheah, K. (2011). Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy. Journal of Materials Chemistry, 21 (8), 2455-2458. https://doi.org/10.1039/c0jm03229h