School of Chinese Medicine
Neurostimulation procedures like vagus nerve stimulation (VNS) and deep brain stimulation have been used to treat refractory epilepsy and other neurological disorders. While holding promise, they are invasive interventions with serious complications and adverse effects. Moreover, their efficacies are modest with less seizure free. Acupuncture is a simple, safe, and effective traditional healing modality for a wide range of diseases including pain and epilepsy. Thalamus takes critical role in sensory transmission and is highly involved in epilepsy genesis particularly the absence epilepsy. Considering thalamus serves as a convergent structure for both acupuncture and VNS and the thalamic neuronal activities can be modulated by acupuncture, we propose that acupuncture could be a promising therapy or at least a screening tool to select suitable candidates for those invasive modalities in the management of refractory epilepsy.
Source Publication Title
Evidence-Based Complementary and Alternative Medicine
Hindawi Publishing Corporation
Copyright © 2014 Shuping Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This work was supported by the intramural grant of China Academy of Chinese Medical Sciences (ZZ03088), General Program of National Natural Science Foundation of China (no. 81273828), and Key Projects of State Basic Research of Ministry of Science and Technology of China (2012CB518503).
Link to Publisher's Edition
Chen, Shuping, Shubin Wang, Peijing Rong, Junling Liu, Hongqi Zhang, and Jianliang Zhang. "Acupuncture for refractory epilepsy: Role of thalamus." Evidence-Based Complementary and Alternative Medicine 2014 (2014): 950631.