Document Type
Journal Article
Department/Unit
Department of Chemistry
Title
Low-potential amperometric detection of dopamine based on MnO2 nanowires/chitosan modified gold electrode
Language
English
Abstract
In this research, a manganese dioxide (MnO2) nanowires/chitosan-modified gold (Au) electrode was successfully fabricated for amperometric determination of dopamine (DA) at a very low working potential (0.00 V vs. SCE). The electrochemical properties of the modified Au electrode were characterized by cyclic voltammetry and electrochemical impedance spectroscopy. The detection scheme was proposed to involve two major reactions: the chemical oxidation of DA to o-dopaminoquinone by MnO2 nanowires, and then the electro-reduction of o-dopaminoquinone to DA at a low working potential (0.00 V vs. SCE), resulting in a distinct reduction response current. The modified Au electrode displays good amperometric response to DA in a wide concentration range 0.10 μM to 1.10 mM. The fabrication of MnO2 nanowires/chitosan-modified Au electrode is simple and highly reproducible (RSD = 3.8%, n = 5). It exhibits excellent analytical performance in terms of low working potential (0.00 V vs. SCE), long shelf-life (90% of its initial response after 1-month storage) and high repeatability (RSD = 2.2%, n = 5). Finally, it was applied to determine DA in real samples directly with high accuracy (99%) and good recovery (99.7-103%), confirming its promising application in routine DA analysis. © 2012 Elsevier Ltd. All Rights Reserved.
Keywords
Dopamine, Low potential, Manganese dioxide, Nanowires, Reduction
Publication Date
2013
Source Publication Title
Electrochimica Acta
Volume
89
Start Page
832
End Page
839
Publisher
Elsevier
DOI
10.1016/j.electacta.2012.11.071
Link to Publisher's Edition
http://dx.doi.org/10.1016/j.electacta.2012.11.071
ISSN (print)
00134686
APA Citation
Huang, Y., Cheng, C., Tian, X., Zheng, B., Li, Y., Yuan, H., Xiao, D., & Choi, M. (2013). Low-potential amperometric detection of dopamine based on MnO2 nanowires/chitosan modified gold electrode. Electrochimica Acta, 89, 832-839. https://doi.org/10.1016/j.electacta.2012.11.071