School of Chinese Medicine
Flos Carthami (FC), the dried flower of Carthamus tinctorius L., has widely been used for the treatment of cardiovascular diseases in China. A rapid fingerprint analysis method of FC was established by ultra-performance liquid chromatography (UPLC) for the quality control. The analysis time was shortened by 45 min, from 75 min on conventional high-performance liquid chromatography (HPLC) to 30 min on UPLC. Ten batches of FC samples from various sources were analyzed by the UPLC method. Coexisting peaks in FC chromatograms were chosen to calculate their relative retention time (RRT) and relative peak area (RPA). Thirteen characteristic peaks were illustrated on UPLC fingerprints. In the 24-h stability test, the relative standard deviation (RSD) for the RRT and RPA was
Source Publication Title
Journal of Chromatographic Science
Oxford University Press
This is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Chromatographic Science following peer review. The version of record Shuo Yu, Lin Zhu, Zhangang Xiao, Jing Shen, Jie Li, Hongshan Lai, Jingjing Li, Hubiao Chen, Zhongzhen Zhao, Tao Yi; Rapid Fingerprint Analysis of Flos Carthami by Ultra-Performance Liquid Chromatography and Similarity Evaluation, Journal of Chromatographic Science, Volume 54, Issue 9, 17 October 2016, Pages 1619–1624, https://doi.org/10.1093/chromsci/bmw115 is available online at: http://dx.doi.org/10.1093/chromsci/bmw115.
This work was supported by the Natural Science Foundation of Guangdong Province (2014A030313766 and 2016A030313008).
Link to Publisher's Edition
Yu, S., Zhu, L., Xiao, Z., Shen, J., Li, J., Lai, H., Li, J., Chen, H., Zhao, Z., & Yi, T. (2016). Rapid fingerprint analysis of flos carthami by ultra-performance liquid chromatography and similarity evaluation. Journal of Chromatographic Science, 54 (9), 1619-1624. https://doi.org/10.1093/chromsci/bmw115