Department of Chemistry
A colorimetric and fluorescent turn-on chemosensor operative in aqueous media for Zn2+ based on a multifunctionalized spirobenzopyran derivative
By conjugating spiropyran chloride 8 with 2-amino-N-(quinolin-8-yl) acetamide (5), multifunctionalized spirobenzopyran derivative SPQN was designed and synthesized as a water soluble colorimetric and fluorescent turn-on chemosensor for Zn2+. In 50% aqueous ethanol buffer solution, SPQN displayed a selective chelation fluorescence enhancement (16-fold) at 650 nm and visible color change (from colorless to red) with Zn2+ among the metal ions examined. In addition, as the third channel to display the metal binding characteristics of SPQN, operating on an efficient FRET process between the quinoline and the merocyanine moiety of the sensor, ratiometric determination of Zn2+ can be realized. © 2010 The Royal Society of Chemistry.
Source Publication Title
Organic and Biomolecular Chemistry
Royal Society of Chemistry
Link to Publisher's Edition
Zhu, Jian-Fa, Han Yuan, Wing-Hong Chan, and Albert W. M. Lee. "A colorimetric and fluorescent turn-on chemosensor operative in aqueous media for Zn2+ based on a multifunctionalized spirobenzopyran derivative." Organic and Biomolecular Chemistry 8.17 (2010): 3957-3964.