Department of Chemistry
Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin
A water-soluble europium(III) complex (1) has been synthesized and demonstrated to be a specific fluorescence probe for the paralytic shellfish toxin saxitoxin, a neurotoxin that blocks the voltage-gated sodium channels on cell membranes. Saxitoxin binds to the europium complex (KB= 6.1×104M-1) and triggers a two-photon induced f-f emission enhancement by over 100% and increases the two-photon absorption crosssection from 9 to 36 GM. © 2011 American Chemical Society.
Source Publication Title
American Chemical Society
Link to Publisher's Edition
He, S., Li, H., Yip, Y., Yeung, C., Fung, Y., Kong, H., Yeung, H., Law, G., Wong, K., Lee, C., Lam, M., Murphy, M., Lam, P., & Wong, W. (2011). Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin. Organic Letters, 13 (19), 5036-5039. https://doi.org/10.1021/ol2018246